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Use of ciprofloxacin in children

St. Luke's Hospital, Bradford, Yorkshire, United Kingdon.

The demographic and subsequent economic pressures in developing nations have contributed to the increasing levels of antibiotic resistance among both commensal flora and apthogenic bacteria. As empirical options are diminishing daily, the role of ciprofloxacin in pediatric infections is becoming inreasingly significant.

OBJECTIVE: The levels of resistance among various enteric pathogens are described, and the efficacy and safety of ciprofloxacin in treating infections such as shigellosis, cholera and Escherichia coli gastroenteritis are discussed. The findings of a large study in invasive salmonellosis in children in rural Africa are briefly presented, including the role of ciprofloxacin in multiresistant invasive disease. In addition the role of ciprofloxacin in multiresistant invasive desease. In addition the role of ciprofloxcin as a chemoprophylactic agent in the control of meningococcal disease is discussed.

RESULT: The efficacy and safety of ciprofloxcin in children were found to be similar to those observed in adults for gatointestinal infectious diseases. Overall the data presented confirm that ciprofloxcin is a safe and efficacious agent for use in children in developing world.

CONCLUSION: Ciprofloxcin has been shown to be safe and efficacious in children in developing countries.

Ref: Pediatr Infect Dis J. 1997 Jan; 16(1):150-9 



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